Director, Operational Excellence

Location: Holly Springs
Posted on: June 23, 2025

Job Description:

FUJIFILM Diosynth Biotechnologies is building the future of bioproduction in Holly Springs, North Carolina. By end of 2025, we’ll open North America’s largest end-to-end CDMO biopharmaceutical manufacturing facility, offering drug substance production, fill-finish, and packaging under one roof. We’re looking for passionate, mission-driven people to help us realize this exciting vision and deliver the next vaccine, cure, or therapy. We offer a dynamic work environment and we’re proud to cultivate a culture that will fuel your purpose, energy, and drive—what we call Genki. Ready to shape the future of medicine? Let’s transform healthcare together! Holly Springs, North Carolina, combines small-town warmth with proximity to Raleigh’s thriving tech scene, making it the perfect blend of community and opportunity. What Youll Do • Defines and leads creation of program to be deployed for Lean Six Sigma principles through the manufacturing facility, including use of tools such as DMAIC, Value Stream Mapping, Kaizen, GEMBAs, 5S. • Hires, Manages, Coaches and develops a strong team of Lean Sigma experts for the site • Defines organization vision and mission, providing a goal for the organization to drive Six Sigma at all levels • Maintains knowledge of industry trends and best practices in Lean Six Sigma methodologies • Partners with cross-functional teams to identify areas for improvement and develop action plans and collaborate to implement process enhancements • Establishes and monitors KPIs to track success of Lean Sigma • Ensures the improvement are standardized and maintained over time through use of visual mgmt., standard work procedures and ongoing audits • Creates and manages processes for sustaining improvements and ensuring that gains are sustained long term • Develops and maintains documentation for process improvement initiatives • Designs and delivers training sessions on Lean Sigma tools for employees at all levels, ensuring understanding and practical application • Acts as Subject Matter Expert (SME) for Lean Sigma methodologies, providing guidance and support as necessary • Mentors and trains staff at all levels on Lean Sigma principles and practices to foster a culture of continuous improvement • Facilitates workshops and meetings to drive continuous improvement efforts • Supports change management processes during the introduction of Lean Sigma tools, methods and initiatives • Overcomes resistance to change by demonstrating the value of process improvements and engaging employees in the transformation journey • Monitors project progress and ensure alignment with organizational goals • Reports on project outcomes and key performance indicators to stakeholder • Prioritizes and manages multiple projects simultaneously, ensuring that timelines, budgets and resources ae effectively aligned with the facility’s operational goals • Develops and implements strategies for eliminating bottlenecks, reducing cycle times and improving throughput • Works closely with department leaders to identify critical areas for improvement and implement actionable solutions • Analyzes data to identify trends, root causes, and improvement opportunities • Creates an environment which enables success including goals, measures, coaching, and communication, among others • Completes required administrative tasks (e.g., timecard approvals, time off approvals, expense reports etc.) • Addresses performance gaps, employee questions and concerns, and partners with HR as needed for resolution • Performs other duties, as assigned Minimum Requirements: • Master’s degree in related field with 11 years of experience; OR • Bachelor’s degree with 13 years of experience; • 10 years of people management, leadership & team management experience • 3 years Lean Sigma leadership experience • 7 years’ experience in GMP manufacturing • Experience in process improvement and project management. • Experience in a similar role, preferably within GMP manufacturing environment • Working knowledge of Lean management principles and Six Sigma methodologies • Experience and proven track record for designing and implementing a Lean Sigma program • Lean Six Sigma Black Belt certification • Strong analytical skills with proficiency in statistical software. Preferred Requirements: • Proven track record of successful process improvement initiatives • Experience in leading cross-functional teams Physical and Work Environment Requirements: • Will work in environment which may necessitate respiratory protection. • May work in Mechanical/Production spaces that may require hearing protection and enrollment in a hearing conservation program. • Ability to discern audible cues. • Ability to stand for prolonged periods of time up to 60 minutes. • Ability to sit for prolonged periods of time up to 240 minutes. • Ability to conduct activities using repetitive motions that include wrists, hands and/or fingers. • Ability to conduct work that includes moving objects up to 10 pounds.

Keywords: , Greensboro , Director, Operational Excellence, IT / Software / Systems , Holly Springs, North Carolina